Protein-protein Interactions in the Cytochrome P450 System
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منابع مشابه
Cloning and gene expression of cytochrome P450 gene from Alcanivorax borkumensis Bacterium
Alcanivorax borkumensis is a marine bacterium that has ability to grow on limited substrates that mainly is alkanes. The ability to use wide range of hydrocarbons is advantage of this bacterium to other marine community bacteria. A. borkumensis have two genetic systems for alkane biodegradation. The First system is alkane hydroxylase (alk-B1and alk-B2) and the second system is...
متن کاملCloning and gene expression of cytochrome P450 gene from Alcanivorax borkumensis Bacterium
Alcanivorax borkumensis is a marine bacterium that has ability to grow on limited substrates that mainly is alkanes. The ability to use wide range of hydrocarbons is advantage of this bacterium to other marine community bacteria. A. borkumensis have two genetic systems for alkane biodegradation. The First system is alkane hydroxylase (alk-B1and alk-B2) and the second system is...
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The aim of this study was to investigate the sub-lethal effects Lead Chloride (PbCl2) on blood indices, liver enzymes, cytochrome P450 gene expression in common carp. For this purpose, Fish with a mean weight of 7 33±0.33 g were prepared and divided into 3 treatments and a control group and exposed to effective concentrations (0.05, 0.15, 0.25 mg / l) of sublethal toxicity for a period of 14 da...
متن کاملBimolecular fluorescence complementation analysis of cytochrome p450 2c2, 2e1, and NADPH-cytochrome p450 reductase molecular interactions in living cells.
Interactions between cytochromes P450 (P450s) and P450 reductase are required for enzymatic activity, and homo- or heterooligomerization of P450s may also be functionally important. Bimolecular fluorescence complementation (BiFC) was used to examine P450 interactions in a natural membrane context within living cells. BiFC detects protein interactions in living cells by reconstitution of a fluor...
متن کاملCYP2D6-CYP2C9 protein-protein interactions and isoform-selective effects on substrate binding and catalysis.
Cytochrome P450 (P450) protein-protein interactions have been observed with various in vitro systems. It is interesting to note that these interactions seem to be isoform-dependent, with some combinations producing no effect and others producing increased or decreased catalytic activity. With some exceptions, most of the work to date has involved P450s from rabbit, rat, and other animal species...
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تاریخ انتشار 2012